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Singapore develops oral insulin nanoparticles as alternative to injections

Singapore develops oral insulin nanoparticles as alternative to injections
Singapore develops oral insulin nanoparticles as alternative to injections
13 January 2021 | News
The NTU team is now in talks with a pharmaceutical company to further improve the nanoparticles’ function
Image credit- NTU Singapore
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.

In a pre-clinical study, the NTU Singapore team fed insulin-containing nanoparticles to rats and found that insulin increased in their blood minutes later.

Delivering insulin orally would be preferable over insulin jabs for patients because it causes less pain than jabs, and could thus lead to improved patient compliance. But oral dosage remains a challenge. As insulin is a protein, it gets broken ....

Subbu Venkatraman , Yusuf Ali , Huang Yingying , Lee Kong Chian School Of Medicine Lkcmedicine , School Of Materials Science , Scientists At Nanyang Technological University , Nanyang Technological University , Materials Science , Lee Kong Chian School , Associate Professor Yusuf Ali , சுபிபு வெங்கட்ராமன் , யூசுப் அலி , பள்ளி ஆஃப் பொருட்கள் அறிவியல் , பொருட்கள் அறிவியல் , லீ காங் சியான் பள்ளி , இணை ப்ரொஃபெஸர் யூசுப் அலி ,

NTU Singapore scientists develop oral insulin nanoparticles that could one day be an alternative to injections

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NTU Singapore scientists develop oral insulin nanoparticles that could one day be an alternative to injections
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.
In a pre-clinical study, the NTU Singapore team fed insulin-containing nanoparticles to rats and found that insulin increased in their blood minutes later.
Insulin therapy is often an important part of treatment for diabetes, a metabolic disease that affects 422 million people globally . In Singapore, the number of diabetics is expected to grow to 1 million – almost a fifth of the population – in 2050 . ....

Subbu Venkatraman , Huang Yingying , Yusuf Ali , Lee Kong Chian School Of Medicine Lkcmedicine , School Of Materials Science , Scientists At Nanyang Technological University , Nanyang Technological University , Materials Science , Lee Kong Chian School , Associate Professor Yusuf Ali , Professor Yusuf Ali , Small Intestine , சுபிபு வெங்கட்ராமன் , யூசுப் அலி , பள்ளி ஆஃப் பொருட்கள் அறிவியல் , பொருட்கள் அறிவியல் , லீ காங் சியான் பள்ளி , இணை ப்ரொஃபெஸர் யூசுப் அலி , ப்ரொஃபெஸர் யூசுப் அலி , சிறிய குடல் , நானோ துகள்கள் , நீரிழிவு நோய் ,

NTU Singapore develops oral insulin nanoparticles that could be an alternative to jabs

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VIDEO: Scientists at NTU Singapore have developed a layer-by-layer insulin nanoparticle that may one day form the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.
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Credit: NTU Singapore
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed insulin nanoparticles that may one day become the basis for an oral medicine, and an alternative to insulin injections for diabetic patients.
In a pre-clinical study, the NTU Singapore team fed insulin-containing nanoparticles to rats and found that insulin increased in their blood minutes later.
Insulin therapy is often an important part of treatment for diabetes, a metabolic disease that affects 422 million people globally . In Singapore, the number of diabetics is expected to grow to 1 million - almost a fifth of the population - in 2050 . ....

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