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Background: While challenges with parenting have been documented for individuals with borderline personality disorder (BPD), the specific mechanisms underlying these challenges are less understood. Further, there is currently a dearth in specialised parenting interventions that have been developed and empirically investigated for this group. This thesis consists of three studies that explore the parenting challenges faced by individuals with BPD and based on these challenges and their proposed underlying mechanisms, proposes a novel parenting intervention. Method: Three mixed methodology studies evaluated the relationship between parenting and BPD. First, an overview of systematic reviews assessed individuals with personality disorder pathology for experiences of maladaptive parenting, and the impact on psychopathological and relational outcomes (Study One). Next, parental stress and competence, personality and mental wellbeing, trauma history, attachment and reflective capacity was ....
Background: Major depressive disorder (MDD) is the most prevalent mental disorder globally, with a greater morbidity rate among females than males. MDD encompasses both psychological and physical symptoms, and is associated with a higher risk of cardiometabolic disease (CMD), encompassing obesity, insulin resistance, dyslipidaemia, and hypertension. This is attributed to shared pathophysiology, including endocrine dysregulation, inflammation, and stress. However, there is limited understanding of the roles of and complex interactions between biological, psychological and physical contributors to the association between MDD and CMD. Prolactin, thyroid hormones, insulin and pro-inflammatory cytokines are implicated in the pathophysiology of both MDD and CMD. Prolactin is associated with stress and weight gain but there is limited research in MDD; cytokines are relevant to the inflammatory theory of MDD but sex differences have not been extensively examined; thyroid hormone dysfunction is ....
Pasadena CA (JPL) Dec 11, 2023 - An international team of researchers spent October and November 2023 in the field studying one of the world s most biologically diverse areas - South Africa s Greater Cape Floristic Region. As part ....
Pasadena CA (JPL) Dec 11, 2023 - An international team of researchers spent October and November 2023 in the field studying one of the world s most biologically diverse areas - South Africa s Greater Cape Floristic Region. As part ....