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Mini-colon and brain organoids shed light on cancer and other diseases

Tiny 3D structures made from human stem cells sometimes offer insights that animal models cannot. Tiny 3D structures made from human stem cells sometimes offer insights that animal models cannot.

Stanford universityUnited statesNew yorkShuibing chenSergiu paMatthiasp lutolfSwiss federal institute of technologySteve gschmeissner science photo libraryWeill cornell medical collegeScience photoSwiss federal institute

MEGA-CRISPR tool gives a power boost to cancer-fighting cells

A system that edits RNA rather than DNA can give new life to exhausted CAR T cells. A system that edits RNA rather than DNA can give new life to exhausted CAR T cells.

United kingdomUnited statesStanford universityUniversity of pennsylvaniaJonathan gootenbergJoseph fraiettaStanley qiSteve gschmeissner science photo libraryMassachusetts institute of technologyScience photoCrystal mackallMassachusetts institute

Turbocharged CAR-T cells melt tumours in mice — using a trick from cancer cells

Immune cells armed with a mutation first identified in cancer cells gain potency but don’t turn cancerous themselves. Immune cells armed with a mutation first identified in cancer cells gain potency but don’t turn cancerous themselves.

United statesSan franciscoJaehyuk choiNick restifoMadeleine duvicKole roybalDrug administrationSteve gschmeissner science photo libraryUniversity of californiaMd anderson cancer centerNorthwestern university in evanstonScience photoCancer centerNorthwestern universityMarble therapeuticsMoonlight bio

How does chronic stress harm the gut? New clues emerge

A bacterium in the intestines of stressed mice interferes with cells that protect against pathogens. A bacterium in the intestines of stressed mice interferes with cells that protect against pathogens.

Xiao zhengUnited statesUniversity of pennsylvaniaChristoph thaissGerard clarkeChina pharmaceutical universitySteve gschmeissner science photo libraryUniversity college corkScience photo library

Living machine? Scientists create biocomputer combining circuits with real human brain tissue

Living machine? Scientists create biocomputer combining circuits with real human brain tissue
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Feng guoSteve gschmeissner science photo libraryNature electronicsUniversity of pisaIndiana universityScience photo libraryAarti ahluwalia