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SABR Leads to Local Control in Primary RCC Without Surgery

Stereotactic ablative body radiotherapy elicited high local control rates in patients with renal cell carcinoma who did not undergo surgical resection.

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Shankar Siva , Peter Maccallum Cancer Centre , Renal Cell Carcinoma , Phase 2 Fastrack Ii Trial Nct02613819 , Stereotactic Ablative Body Radiotherapy ,

SABR to Oligoprogressive Lesions Delays Change in Systemic Therapy in ER+ Advanced Breast Cancer

Administration of stereotactic ablative body radiotherapy to oligoprogressive lesions delayed a change in systemic therapy in patients with estrogen receptor–positive/HER2-negative breast cancer enrolled to the prospective phase 2 AVATAR trial.
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Palbociclib Ibrance , Steven David , Peter Maccallum Cancer Centre , Breast Cancer , Stereotactic Ablative Body Radiotherapy , Oligoprogressive Lesions , Er Positive Breast Cancer , Avatar Trial , Astro Annual Meeting ,

"A Monte Carlo study to evaluate and optimise the angular dependence of" by Ilia Filipev, Giordano Biasi et al.

Purpose: A detector assembly based on a 2D silicon array sensor, Octa, was previously demonstrated to be accurate for small field relative dosimetry. Experimental studies showed angular dependence of the response that has also variations with the field size. A Monte Carlo simulation model was developed and used in this work to study how the detector assembly's components contribute to the observed angular dependence. Methods: Geant4 was used as the Monte Carlo code. A detailed model of the Octa detector and its packaging was placed in the centre of a solid water phantom with the central sensitive volumes (SVs) located at the isocentre and irradiated at polar angles from 0 to 180° (the beam was normal to the detector plane at 0°). Phase-space files from the IAEA database were used to model a CyberKnife X-ray beam with collimator diameters of 5, 10, and 15 mm. Reference simulations were compared with previous experimental results. To investigate the impact of the assembly's m ....

Monte Carlo , Cyberknifex Ray , 2d Monolithic Silicon Array Detector , Angular Dependence , Monte Carlo Simulation , Mall ﬁeld Dosimetry , Stereotactic Ablative Body Radiotherapy ,