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Metabotropic Glutamate Receptor 5 Is Alzheimer's Missing Link, Says Study

Researchers have discovered a protein that is the missing link in the complicated chain of events that lead to Alzheimer s disease. They also found that blocking the protein with an existing drug can restore memory in mice with brain damage that mimics the disease. ....

Mikhail Kostylev , Stephen Strittmatter , Thomas Wisniewski , Meghane Kerrisk , Hideyuki Takahashi , Stephenm Strittmatter , Anthonyj Koleske , Haakonb Nygaard , Jacquelinek Heiss , Erikc Gunther , Adamc Kaufman , Alexander Vortmeyer , Yale University School , Medicine Professor , Massimiliano Stagi , Metabotropic Glutamate Receptor , Oligomer Bound , Cellular Prion Protein ,

Allyx Therapeutics to Present Phase 1 Data for Lead Compound ALX-001 at the 16th Clinical Trials on Alzheimer's Disease Meeting

Allyx Therapeutics to Present Phase 1 Data for Lead Compound ALX-001 at the 16th Clinical Trials on Alzheimer's Disease Meeting
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Stephen Strittmatter , Bristol Meyers Squibb , Tim Siegert , Eliza Schleifstein , Yale University , Alzheimer Association , National Institutes Of Health , Neuroscience At Yale School Of Medicine , Bristol Myers Squibb , Present Phase , Lead Compound , Clinical Trials , Clinical Data , National Institutes , Adam Mecca , Yale School , Medicine Alzheimer , Disease Research , Allyx Therapeutics , Professor Strittmatter ,

Endolysosomal TMEM106b Regulates Myelin Lipid Metabolism

Endolysosomal TMEM106b Regulates Myelin Lipid Metabolism
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Yale University , United States , New Haven , New South Wales , Markus Damme , Anthony Don , Atpase Sep , Stephen Strittmatter , Chelsea Weidman Burke , Hideyuki Takahashi , Yale University School Of Medicine , University Of Kiel , University Of Sydney , Yale University School , Chelsea Weidman ,