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DNA test to predict odds of severe COVID-19 draws scrutiny

Science s COVID-19 reporting is supported by the Heising-Simons Foundation



For people not yet vaccinated against COVID-19 or still nervous about venturing into crowds, the sales pitch may be alluring: Drool into a tube to provide your DNA and mail it off to see how likely you are to be among the 10% to 15% of people who will end up in the hospital or die from a SARS-CoV-2 infection. That s the promise of a $175 test an Australian company launched last week in the United States. It combines genetic data with someone s age, sex, and preexisting medical conditions to predict their risk of becoming extremely ill from COVID-19.

The firm developed its test using data on thousands of COVID-19 patients in the United Kingdom. It may be a forerunner of similar risk tests: An academic team has recently detailed a simpler genetic test to help determine how aggressively some people infected with SARS-CoV-2 should be treated.

Yet several genetics experts warn that how a ....

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