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Novel liver dialysis device yields 'rapid clinical effect' in patients with liver failure

The Dialive device significantly reduced severity of endotoxemia and improved albumin function in patients with acute-on-chronic liver failure and appears safe with careful patient monitoring, according to data in the Journal of Hepatology.
“Dialive is a novel liver dialysis device invented at University College London,” Rajiv Jalan, PhD, lead investigator and professor of hepatology ....

Rajiv Jalan , Steffen Mitzner , Digestive Health , Rostock University Medical Center , University College London , Institute For Liver , Chronic Liver Failure ,

New liver dialysis device shows potential to resolve liver failure in patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year. Currently, the only potential treatment for this condition is liver transplantation, which is available to very few patients. A first-in-human randomized controlled clinical trial using DIALIVE, a novel liver dialysis device, demonstrated its potential as a disease-modifying therapy and resolved liver failure significantly faster and in a greater p. ....

City Of , United Kingdom , Comunidad Autonoma De Cataluna , Phillip Lavin , Vanessa Stadlbauer , Rahul Kumar , Agustin Albillos , Alexandru Chivu , Sebastian Koball , Jan Stange , Luis Ib , Georg Lamprecht , Banwari Agarwal , Andrew Davenport , Mohammed Sheikh , Margret Paar , Amir Gander , Faouzi Saliba , Jeremy Cordingley , Dana Rodica Tomescu , Javier Fernandez , Vicente Arroyo , Rafael Ba , Gema Domenech , Gavin Wright , Rajiv Jalan ,

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year. ....

City Of , United Kingdom , Comunidad Autonoma De Cataluna , Carrie Morgan , Nathan Davies , Banwari Agarwal , Megan Craig , Rajiv Jalan , Steffen Mitzner , Division Of Gastroenterology , University College London , Department Of Medicine , Yaqrit Discovery Ltd , Rostock University Medical Center , Institute For Liver Digestive Health , Digestive Health , Royal Free Hospital , European Foundation , Chronic Liver Failure , Royal Free , Vice President , Clinical Operations , Clinical Trial , Liver Transplantation ,