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Study proposes streamlined approach to developing cancer drugs

Drug discovery can be a frustrating process of trial and error.

David heppnerBrandon olignySurbhi chitnisTahereh damghaniStefan lauferCalvin phamAssayquant technologies incUniversity at buffaloNational institutes of healthHarvard medical schoolUb college of artsRoswell park comprehensive cancer centerHub technologyEberhard karls universityUniversity of eastern finlandCommunications chemistry

Proposed Streamlined Approach Revolutionizes Cancer Drug Development

Proposed Streamlined Approach Revolutionizes Cancer Drug Development
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Brandon olignyStefan lauferDavid heppnerTahereh damghaniSurbhi chitnisCalvin phamEberhard karls universityUb college of artsNational institutes of healthRoswell park comprehensive cancer centerAssayquant technologies incHub technologyHarvard medical schoolUniversity of eastern finlandUniversity at buffaloCommunications chemistry

Study proposes streamlined approach to developing cancer drugs

Study proposes streamlined approach to developing cancer drugs
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Douglas levere univeristyTahereh damghaniKristopherw hoytSurbhi chitnisStefan lauferFlorian wittlingerCalvin phamBrandon olignyDavid heppnerUniversity at buffaloHub technologyUb college of artsRoswell park comprehensive cancer centerDouglas levere university at buffaloNatural sciencesHarvard medical school

UB research may offer a more streamlined approach to developing cancer drugs

Drug discovery can be a frustrating process of trial and error.

Brandon olignyTahereh damghaniSurbhi chitnisCalvin phamStefan lauferDavid heppnerUniversity at buffaloAssayquant technologies incUb college of artsEberhard karls universityHub technologyCommunications chemistryNational institutes of healthHarvard medical schoolRoswell park comprehensive cancer centerUniversity of eastern finland

Study provides atomistic level insight into target residence time of small molecule kinase inhibitors

When a drug molecule binds to its target protein, it stays bound for some time before eventually unbinding the target. The actual time how long a drug molecule resides bound to its target varies among compounds.

Aimee molineuxStefan lauferTatu pantsarNature communicationsUniversity of eastern finlandEastern finlandSenior researcherLead authorKinase inhibitor