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Janssen: New Amivantamab Data from CHRYSALIS Study Show Robust Clinical Activity and Durable Responses in Patients with Metastatic or Unresectable Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Mutations


Janssen: New Amivantamab Data from CHRYSALIS Study Show Robust Clinical Activity and Durable Responses in Patients with Metastatic or Unresectable Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Mutations
FOR EU TRADE AND MEDICAL MEDIA ONLY Not for distribution in the UK and Benelux
The Janssen Pharmaceutical Companies of Johnson Johnson today announced new data from the Phase 1 CHRYSALIS study, which evaluated amivantamab in patients with metastatic or unresectable non-small cell lung cancer (NSCLC) and epidermal growth factor receptor (EGFR) exon 20 insertion mutations whose disease progressed on or after platinum-based chemotherapy.
1 These data were presented for the first time in an oral presentation at the International Association for the Study of Lung Cancer s (IASLC) 2020 World Conference on Lung Cancer (WCLC) Singapore. The key findings showed robust activity and durable responses with a tolerable and manageable safety profile (Abstract #3031) in patien ....

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Istari Oncology Announces FDA Grants Orphan Drug Designation for PVSRIPO for the Treatment of Advanced Melanoma


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Istari Oncology Announces FDA Grants Orphan Drug Designation for PVSRIPO for the Treatment of Advanced Melanoma
Istari Oncology Announces FDA Grants Orphan Drug Designation for PVSRIPO for the Treatment of Advanced Melanoma
Istari Oncology, Inc., a clinical-stage biotechnology company, today announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for PVSRIPO for the treatment of advanced melanoma (stage IIB-IV). PVSRIPO is a novel viral immunotherapy, based on the Sabin type 1 polio vaccine, that activates a patients innate and adaptive immune system to facilitate an anti-tumor response and establish long-term immunologic memory to help prevent the cancers return. ....

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GT Biopharma Announces TriKE™ For The Treatment Of Breast And GI Cancers


GT Biopharma Announces TriKE™ For The Treatment Of Breast And GI Cancers
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BEVERLY HILLS, Calif., Dec. 28, 2020 /PRNewswire/ GT Biopharma, Inc. (OTCQB: GTBP) (GTBP.PA) an immuno-oncology company focused on innovative therapies based on the Company s proprietary NK cell engager (TriKE™) technology platform is pleased to announce the filing of U.S. and international patent applications, and the initiation of clinical development of TriKE™ therapy for the treatment of HER2+, HER3+ and HER2+/HER3+ heterodimer complex breast and gastrointestinal cancers.
Building upon the success of GTB-3550, where in FDA clinical trials patient #7 showed a 61.7% reduction in cancer cells for high-risk Myelodysplastic Syndromes (HR-MDS), GT Biopharma is expanding the therapeutic utility of its TriKE™ platform to attack solid tumor cancers.  The Company s HER2 TriKE is based on its modular therapeutic platform, which is ....

United States , Anthony Cataldo , Beverly Hills , Andrew Barwicki , Prnewswire Gt Biopharma Inc , Source Gt Biopharma Inc , National Cancer Institute , World Health Organization , Exchange Commission , University Of Minnesota , Gt Biopharma Inc , Myelodysplastic Syndromes , Chief Executive Officer , World Health , Securities Act , Cancer Institute , Statistics Review , ஒன்றுபட்டது மாநிலங்களில் , அந்தோணி காதலிடோ , பெவர்லி மலைகள் , தேசிய புற்றுநோய் நிறுவனம் , உலகம் ஆரோக்கியம் ஆர்கநைஸேஶந் , பரிமாற்றம் தரகு , பல்கலைக்கழகம் ஆஃப் மினசோட்டா , தலைமை நிர்வாகி அதிகாரி , உலகம் ஆரோக்கியம் ,