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Oral TXA is equally efficacious at preventing blood loss in orthopedic surgery, interim study suggests

Interim results of a study conducted by researchers at Hospital for Special Surgery (HSS) suggest that oral tranexamic acid (TXA) is non-inferior to intravenous (IV) TXA in preventing blood loss in total knee and total hip replacement surgery. ....

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Risk Factors for Pediatric Opioid Dependence After Surgery

Risk Factors for Pediatric Opioid Dependence After Surgery
by Colleen Fleiss on
May 14, 2021 at 11:10 PM
Key risk factors for persistent opioid use after surgery in pediatric patients have been discovered by Hospital for Special Surgery (HSS) researchers. Study findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.
Pediatric patients have developing brains that are uniquely vulnerable to addiction, and we need to learn to treat their pain safely without putting them at additional risk for opioid misuse, said principal investigator Kathryn (Kate) DelPizzo, MD, an anesthesiologist at HSS.
It is therefore critical for clinicians to understand risk factors for opioid dependence in this vulnerable population, and to develop strategies to prevent long-term opioid use. ....

United States , Kathryn Kate Delpizzo , Spring American Society Of Regional Anesthesia , Special Surgery , American Society , Regional Anesthesia , Pain Medicine , Pediatric Patients , ஒன்றுபட்டது மாநிலங்களில் , சிறப்பு அறுவை சிகிச்சை , அமெரிக்கன் சமூகம் , பிராந்திய மயக்க மருந்து , வலி மருந்து ,

Study of hip fracture patient characteristics and outcomes pre- and post-COVID-19 outbreak

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The COVID-19 pandemic has been shown to have caused a significant strain on the healthcare system and resources in the United States. However, data regarding the impact of the virus on hip fractures, primarily seen in elderly patients, is lacking.
Researchers at Hospital for Special Surgery (HSS) sought to compare characteristics and outcomes of hip fracture patients admitted during the COVID-19 outbreak to patients admitted before the outbreak. They also examined characteristics and outcomes of hip fracture patients with and without the virus. Their findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1 ....

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Interim study suggests oral TXA is equally effective in preventing blood loss in joint replacement

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Interim results of a study conducted by researchers at Hospital for Special Surgery (HSS) suggest that oral tranexamic acid (TXA) is non-inferior to intravenous (IV) TXA in preventing blood loss in total knee and total hip replacement surgery. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.1
Previously available information suggests that oral, IV and topical TXA are all effective at reducing blood loss and drastically reducing blood transfusion rates during and after surgery, but research with direct comparisons for each method is limited.
TXA in orthopedic surgery has become the standard of care. However, the most efficient, efficacious and cost effective method of administration remains unknown, said principal investigator Stavros Memtsoudis, MD, PhD, MBA, an anesthesiologist at HSS. The oral administration of TXA is logistically easier, thus reducing the risk of drug error ....

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HSS researchers find duloxetine may reduce opioid use after total knee replacement

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In a study conducted by researchers at Hospital for Special Surgery (HSS), cumulative opioid use was reduced by 30% in a patient group that received duloxetine after total knee arthroplasty (TKA) compared with patients who received placebo. Patients who received duloxetine also reported higher pain management satisfaction and less pain interference with mood, walking, normal sleep, and work activities. These findings were presented at the 2021 Spring American Society of Regional Anesthesia and Pain Medicine (ASRA) Annual Meeting.
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Studies have demonstrated that many patients report joint pain two weeks after TKA.
2 Given the status of the ongoing opioid epidemic, it is critical to study safe and effective alternative pain treatments. ....

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