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Novavax COVID-19 Vaccine


Novavax COVID-19 Vaccine (NVX-CoV2373) Description
Novavax COVID-19 vaccine (NVX-CoV2373) (Covovax) is a prefusion protein coronavirus vaccine candidate made using Novavax’s proprietary nanoparticle technology, Matrix-M, an adjuvant to enhance immune responses and stimulate high levels of neutralizing antibodies.
Novavax Inc. s NVX-CoV2373 vaccine candidate creates an engineered baculovirus containing a gene for a modified SARS-CoV-2 spike protein. The baculovirus then infects a culture of Sf9 moth cells, which create the spike protein and display it on their cell membranes. The spike proteins are then harvested and assembled onto a synthetic lipid nanoparticle about 50 nanometers across, each displaying up to 14 spike proteins. ....

United States , United Kingdom , North Carolina , South Africa , Barnard Castle , New Zealand , South Korea , Commonwealth Of Australia , Republic Of Korea , Franciss Collins , Karen Kotloff , Stanleyc Erck , Gregorym Glenn , Anthonys Fauci , Wayneai Frederick , Adar Poonawalla , Us Department Of Defense , Department Of Defense , Takeda Pharmaceutical Company Limited , Ministry Of Health , Baxter International Inc , Baxter Biopharma Solutions , Serum Institute Of India Private , Vaccine Alliance , Takeda Pharmaceutical Company , Coalition For Epidemic Preparedness Innovations ,

Joint Committee on Vaccination and Immunisation: advice on priority groups for COVID-19 vaccination, 30 December 2020


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Introduction
The Joint Committee on Vaccination and Immunisation (
JCVI) advises that the first priorities for the current COVID-19 vaccination programme should be the prevention of COVID-19 mor ....

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NVX-CoV2373 COVID-19 Vaccine


NVX-CoV2373 COVID-19 Vaccine Description
NVX-CoV2373 is a prefusion protein coronavirus vaccine candidate made using Novavax’s proprietary nanoparticle technology, Matrix-M, an adjuvant to enhance immune responses and stimulate high levels of neutralizing antibodies.
Novavax’s patented saponin-based Matrix-M adjuvant has demonstrated a potent and well-tolerated effect by stimulating the entry of antigen-presenting cells into the injection site and enhancing antigen presentation in local lymph nodes, boosting immune response and helping an immunized person make antibodies against the virus.
Novavax identified the recombinant nanoparticle NVX‑CoV2373 vaccine as its lead COVID-19 candidate following pre-clinical testing that demonstrated high immunogenicity and high levels of neutralizing antibodies. ....

United States , North Carolina , United Kingdom , South Africa , University Of Maryland School Medicine , New Zealand , South Korea , Commonwealth Of Australia , Republic Of Korea , Franciss Collins , Shabir Madhi , Karen Kotloff , Gregorym Glenn , Stanleyc Erck , Halle Westfalen , Anthonys Fauci , Us Department Of Defense , Department Of Defense , Ministry Of Health , Melinda Gates Foundation , Baxter International Inc , Baxter Biopharma Solutions , Serum Institute Of India Private , National Health Service , Coalition For Epidemic Preparedness Innovations , Wits University ,