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McGill University While previous research early in the pandemic suggested that the vitamin D cuts the risk of contracting COVID-19, a new study from McGill University finds there is no genetic evidence that the vitamin works as a protective measure against the coronavirus. “Vitamin D supplementation as a public health measure to improve outcomes is not supported by this study. Most importantly, our results suggest that investment in other therapeutic or preventative avenues should be prioritized for COVID-19 randomized clinical trials,” say the authors. To assess the relationship between vitamin D levels and COVID-19 susceptibility and severity, the researchers conducted a Mendelian randomization study using genetic variants strongly associated with increased vitamin D levels. They looked at genetic variants of 14,134 individuals with COVID-19 and over 1.2 million individuals without the disease from 11 countries. ....
While previous research early in the pandemic suggested that vitamin D cuts the risk of contracting COVID-19, a new study from McGill University finds there is no genetic evidence that the vitamin works as a protective measure against the coronavirus. ....
Read Time: Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19. Using drugs that boost OAS1 levels could be explored to try to improve these outcomes. The findings are published today in âOur analysis shows evidence that OAS1 has a protective effect against COVID-19 susceptibility and severity,â explains Dr. Brent Richards, a senior investigator at the LDIâs Centre for Clinical Epidemiology and Professor of Medicine, Human Genetics, Epidemiology and Biostatistics at McGill University. âThis is a very exciting development in the race to identify potential therapies to treat patients because there are already therapies in pre-clinical development that boost OAS1 and could be explored for their effect against SARS-CoV-2 infection.â ....