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Inside the new mRNA vaccines for COVID-19
How the Pfizer and Moderna vaccines work to prime the human immune system to fight SARS-CoV-2 By Jim Fessenden December 18, 2020
Health care workers across the nation this week are the first Americans to receive the new mRNA vaccine by Pfizer/BioNTech to protect against COVID-19, and the Moderna vaccine appears soon to follow, with emergency approval by the Food and Drug Administration possible any day. The new mRNA vaccines are the first of their kind and researchers at UMass Medical School are among the leading RNA biologists in the world. The Medical School is home to the
UMMS study shows how novel mechanism in P. aeruginosa bacteria disables ribosome
Understanding of biological process could lead to potential therapeutic for disabling protein synthesis in tumor cells By Jim Fessenden December 11, 2020
A new study by Alejandro Vasquez-Rifo, PhD, and Victor Ambros, PhD, shows that certain strains of
Pseudomonas aeruginosa, a rod-shaped bacterial pathogen that causes disease in plants and animals, including humans, have a unique mechanism for disabling and degrading the ribosome in its host cells. The study, published in
PLOS Biology, points to a mechanism that may be harnessed by scientists in the lab or by clinicians to target tumor cells or perhaps even block the mechanisms that make certain pathogens virulent.