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Osimertinib and chemotherapy is more effective than osimertinib alone as first-line treatment for EGFR-mutant, advanced NSCLC, phase 3 data suggest. ....
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Pembrolizumab led to sustained improvements in recurrence-free survival and distant metastasis-free vs placebo as adjuvant therapy in patients with resected stage IIB or IIC melanoma ....
Adagrasib induced high overall response rates in patients with KRAS G12C–mutated non–small cell lung cancer who achieved at least 90% mutation allele frequency clearance. ....