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Chances of eliminating HIV infection increase

EMBARGO UNTIL: May 1, 2023 at 3 PM ET
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection, new research from the Lewis Katz School of Medicine at Temple University and the University of Nebraska Medical Center (UNMC) shows. The study, published online in the journal The Proceedings of the National Academy of Sciences (PNAS), is the first to combine a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1. ....

United States , University Of Nebraska Medical Center , Shohreh Amini , Howard Gendelman , Saumi Mathews , Santhi Gorantla , Emiko Waight , Lili Guo , Chen Zhang Sruthi Sravanam , Laurah Carnell , Rafal Kaminski , Benson Edagwa , Shuren Liao , Pietro Mancuso , Maurizio Caocci , Chong Liu , Howarde Gendelman , Triciah Burdo , Brady Sillman , Kamel Khalili , Rahsan Sariyer , Tricia Burdo , University Of Nebraska System , National Institutes Of Health , Department Of Microbiology , Katz School Of Medicine ,