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Cureus | Magnitude of Extended-Spectrum Beta-Lactamase-Producing Gram-Negative and Beta-Lactamase-Producing Gram-Positive Pathogens Isolated from Patients in Dar es Salaam, Tanzania: A Cross-Sectional Study

Background

The worldwide emergence of antibiotic-resistant bacteria threatens to overshadow the dramatic advances in medical sciences since the discovery of antibiotics. Antibiotic resistance has rendered some antibiotics obsolete, creating a reliance on synthetic drugs. In some instances, bacteria can be resistant to all antibiotics. The problem of antibiotic resistance is eminent in resource-limited countries like Tanzania, where systematic surveillance and routine susceptibility tests are rarely conducted. Therefore, this study aimed to investigate the magnitude of beta-lactamase-producing Gram-positive pathogens and Enterobacteriaceae with extended-spectrum beta-lactamase (ESBL) in Dar es Salaam, Tanzania.

Methodology

This multi-site cross-sectional study involved three private hospitals in Dar es Salaam, Tanzania. The study was conducted between July and September 2008. Bacterial isolates were collected, identified, and subjected to antibiotic-sensitivit ....

United States , Dar Es Salaam Region , Dar Es Salaam , United Kingdom , Msimbazi River , Keko Machungwa , Regency Medical Centre , Laboratory Of Microbiology , Clinical Laboratory , Muhimbili University Of Health , Standards Institute , Microbiology At Muhimbili University Of Health , Statistical Package For The Social Sciences , Alkem Lab , Saharan Africa , Shree Hindu Mandal , Massana Hospitals , Pharmaceutical Microbiology , Muhimbili University , Allied Sciences , Peptone Water , Statistical Package , Social Sciences , Institutional Review Board , Msimbazi River Basin Ecosystem ,