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Innovative Tool Enhances Disease-Causing Gene Hunt

Innovative Tool Enhances Disease-Causing Gene Hunt
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Kaixuan Luo , Matthew Stephens , Wesley Crouse , Sheng Qian , Ralphw Gerard , University Of Chicago , Nature Genetics , Associate Professor , Human Genetics , Transcriptome Wide Association , Siming Zhao ,

New tool improves the search for genes that c

<p>A new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. The tool, described in a new paper published January 26, 2024, in <em>Nature Genetics</em>, combines data from genome wide association studies (GWAS) and predictions of genetic expression to limit the number of false positives and more accurately identify causal genes and variants for a disease.</p>
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Sheng Qian , Wesley Crouse , Ralphw Gerard , Kaixuan Luo , Matthew Stephens , Method Of Research , University Of Chicago , Nature Genetics , Associate Professor , Human Genetics , Transcriptome Wide Association , Siming Zhao ,