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Study shows how senescent cells can be an underlying cause of kidney damage

A study in mice by researchers at Georgetown Lombardi Comprehensive Cancer Center has found that stress and tissue damage initiated by angiotensin II, a molecule that is known to increase blood pressure and stiffening in the linings of blood vessels, leads to cellular senescence, a process by which a cell ages and permanently stops dividing but does not die. ....

Shaunt Mehdikhani , Margarida Mendenoca , William Welch , Bhaskar Kallakury , Emily Henderson , Anton Wellstein , Irfan Khan , Moshe Levi , Marcelo Schmidt , Annat Riegel , Sidharth Jain , Christophers Wilcox , Georgetown University , Georgetown University Institutional Funds , Georgetown Lombardi Comprehensive Cancer Center , Hypertension Foundation , Developmental Biology , Tumor Biology , Georgetown Lombardi , Georgetown University Institutional , Blood Pressure , Blood Vessels , Developmental Biology , High Blood Pressure ,