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"Cannabis Dependence is Associated with Reduced Hippocampal Subregion V" by Valentina Lorenzetti, Alexandra Gaillard et al.

Background: Males and females who consume cannabis can experience different mental health and cognitive problems. Neuroscientific theories of addiction postulate that dependence is underscored by neuroadaptations, but do not account for the contribution of distinct sexes. Further, there is little evidence for sex differences in the neurobiology of cannabis dependence as most neuroimaging studies have been conducted in largely male samples in which cannabis dependence, as opposed to use, is often not ascertained. Methods: We examined subregional hippocampus and amygdala volumetry in a sample of 206 people recruited from the ENIGMA Addiction Working Group. They included 59 people with cannabis dependence (17 females), 49 cannabis users without cannabis dependence (20 females), and 98 controls (33 females). Results: We found no group-by-sex effect on subregional volumetry. The left hippocampal cornu ammonis subfield 1 (CA1) volumes were lower in dependent cannabis users compared with non- ....

Addiction Working Group , Sex Differences ,

Study finds women with depression face higher cardiovascular risk than men

Study finds women with depression face higher cardiovascular risk than men
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Hidehiro Kaneko , University Of Tokyo , Association Between Depression , Sex Differences , Incident Cardiovascular Disease ,