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New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias. ....

United States , Sri Lanka , Jose Mar , Generalitat Valenciana , Excellence Program , Spanish Agency Of Medicaments , University Professors , Spanish National Research Council , Global Health Interdisciplinary Platform , Health Products , Severo Ochoa Center , National Phase , Universitat Polit , Pablo Botella , Spanish Agency , South East , Resilience Facility , Global Health Platform , Jesus San Miguel , Universidad De Navarra , Anti Inflammatory , Covid 19 , Fatty Liver , Global Health , Immune Response , Liver Disease ,

The promise of novel FolRα-targeting antibody

Presented today by VHIO’s Ana Oaknin at the 2023 ASCO Annual Meeting, 2-6 June (Chicago, IL), updated dose expansion data of the STRO-002-GM1 global phase I study show promise of FolRα-targeting antibody drug conjugate (ADC) luveltamab tazevibulin in patients with recurrent FolRα-expressing epithelial ovarian cancer. ....

Israel General , United States , Craig Berman , Hatem Dokainish , David Omalley , Lin Liu , Carmen Garc , Lainie Martin , John Diaz , Jesus Garcia , Alexander Spira , Russell Schilder , Michael Palumbo , Christina Annunziata , Denise Uyar , Tanja Pejovic , John Moroney , Caixa Foundation , Hebron Institute Of Oncology , Severo Ochoa Center , Gynecological Malignancies Group , Research Centres Of Catalonia , Hebron University Hospital , Ana Oaknin , Principal Investigator , Hebron Institute ,