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Decoding the autoantibody reactome

Decoding the autoantibody reactome
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List: Top 16 Pioneers in Biotech Venture Capital

These 16 biotech investors are all in their first decade of working in venture capital and bringing fresh perspectives to the world of biotech. ....

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'Turncoat' antibodies are major culprits in severe COVID-19

Rogue antibodies are major culprits in severe cases of COVID-19, researchers report.
These autoantibodies target and react with a person’s tissues or organs similar to ones that cause autoimmune diseases such as lupus or rheumatoid arthritis. In COVID-19 cases they can attack healthy tissue in brain, blood vessels, platelets, liver, and the gastrointestinal tract, researchers report. The more autoantibodies detected, the greater the disease severity patients experience.
And the autoantibodies paradoxically also target and interfere with many immune system proteins that are designed to fend off infections, according to a new study.
The development of antibodies in response to the COVID-19 virus has been the great long-term hope for ending the pandemic, but it might not be so simple. ....

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Rogue antibodies wreak havoc in severe COVID-19 cases

By Bill Hathaway
May 19, 2021
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The development of antibodies to the COVID-19 virus has been the great long-term hope of ending the pandemic. However, immune system turncoats are also major culprits in severe cases of COVID-19, Yale scientists report in the journal Nature.
These autoantibodies target and react with a person’s tissues or organs similar to ones that cause autoimmune diseases such as lupus or rheumatoid arthritis. In COVID-19 cases they can attack healthy tissue in brain, blood vessels, platelets, liver, and the gastrointestinal tract, researchers report. The more autoantibodies detected, the greater the disease severity experienced by patients. ....

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Biogen and LabCentral Award Two Golden Tickets to Local and Innovative Science Startups

Golden Tickets winners Bolden Therapeutics and Seranova Bio will have access to a state-of-the-art lab facilities at LabCentral with mentorship and support from Biogen CAMBRIDGE, Mass., Feb. 11, 2021 (GLOBE NEWSWIRE) Biogen Inc. (Nasdaq: BIIB) and LabCentral today announced Bolden Therapeutics and Seranova Bio as the recipients of Biogen’s Golden Tickets, an initiative offering promising winning startups one year of lab space accompanied by continued mentorship from Biogen. LabCentral is a first-of-its-kind shared laboratory space designed as a launchpad for high-potential life-sciences and biotech startups. As a platinum-level sponsor of the program, Biogen demonstrates its ongoing commitment to innovation and support for the local biotech community by awarding Golden Tickets to two companies each year. This includes up to one year of the benefits of LabCentral’s shared infrastructure and services. “For people living with diseases that impact the central nervous ....

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