Scientists demonstrate a promising strategy for treating lymphomas
Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.
The new approach uses natural cancer-targeting immune cells, known as natural killer cells, that have been modified to selectively target lymphoma. As described in their study, published in the journal
Angewandte Chemie, the modified natural killer cells brought about a dramatic reduction of lymphoma in a mouse. We found a way to achieve selectivity in targeting lymphoma cells, which is an important departure from existing therapies, says co-senior author Peng Wu, PhD, an associate professor in the Department of Molecular Medicine at Scripps Research.
E-Mail
IMAGE: A heavy layer of glycans, seen here in green, cover immune cells and provide a way to target cancer-specific markers in the body. view more
Credit: Image courtesy of Senlian Hong, Wu Lab at Scripps Research
LA JOLLA, CA Scientists at Scripps Research have demonstrated a promising new strategy for treating lymphomas, a group of cancers that begin in infection-fighting cells of the immune system called lymphocytes.
The new approach uses natural cancer-targeting immune cells, known as natural killer cells, that have been modified to selectively target lymphoma. As described in their study, published in the journal
Angewandte Chemie, the modified natural killer cells brought about a dramatic reduction of lymphoma in a mouse.