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Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment. ....

United States , Naohiro Inohara , Jiali Yu , Weiping Zou , Masanori Matsumoto , Ilona Kryczek , Ryosuke Sato , Gabriel Nunez , Linda Vatan , Roberta Caruso , Michaelh Shaw , Yuying Xie , Colitis Foundation , Takeda Millennium Pharmaceuticals , University Of Michigan Health Rogel Cancer Center , University Of Michigan , National Institutes Of Health , Canadian Institutes Of Health , National Science Foundation , Takeda Pharmaceuticals , Rogel Cancer Center Shared Resources , Michigan Health Rogel Cancer Center , Senior Study Author , Paul De Kruif Professor , National Institutes , Canadian Institutes ,

New atlas characterizes cellular landscape of the early human limb

Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured for the first time as scientists unveil a spatial cell atlas of the entire developing human limb, resolved in space and time. ....

Sarah Teichmann , Hongbo Zhang , Wellcome Sanger Institute , Sun Yat Sen University , European Bioinformatics Institute , Wellcome Sanger , Image Credit , Bioinformatics Institute , Human Cell Atlas , Senior Study Author ,

New technique developed to rapidly detect genetic changes in malaria parasites

Scientists have developed a technique to rapidly and reliably detect genetic changes in malaria parasites in Ghana, using just a gaming laptop and portable MinION sequencer from Oxford Nanopore. ....

Greater Accra , Edem Adika , Lucas Amenga Etego , Oxford Nanopore , Lily Ramsey , Wellcome Sanger Institute , University Of Ghana , Nature Microbiology , William Hamilton , Senior Study Author , Wellcome Sanger , West African Centre , Cell Biology , Infectious Pathogens , Saharan Africa ,

A Potential Treatment for Glioblastoma Using Nanoparticle

A novel nanoparticle treatment for glioblastoma has been developed by Northwestern Medicine investigators, as per the research published in Nature Communications. ....

United States , Xpeng Zhang , Skyla Baily , Maciej Lesniak , Michaelj Marchese , National Institutes Of Health Cancer Institute , Roberth Lurie Comprehensive Cancer Center , Nature Communications , Northwestern University , National Brain Tumor Society , Northwestern Medicine , Image Credit , National Brain Tumor , Study First Author , Assistant Professor , Neurological Surgery , Senior Study Author , Comprehensive Cancer Center , National Institutes , National Cancer Institute , Northwestern Brain Tumor , National Academy ,

Researchers discover a key player in preventing 'insulin shock'

Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for type 2 diabetes, as well. ....

University Of California San Diego , United States , San Diego , Ali Gu , Yahui Zhu , Michael Karin , Emily Henderson , Uc San Diego School Of Medicine , American Diabetes Association , American Diabetes , Cell Metabolism , California San Diego School , Senior Study Author , Distinguished Professor , Diego School , Chongqing University , Cell Metabolism , Fatty Liver , Insulin Shock , Type 1 Diabetes , Type 2 Diabetes ,