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Circadian clock can be leveraged to enhance cancer immunotherapy

A multidisciplinary research team has revealed that the circadian clock the biological pacemaker that governs daily rhythms in physiological processes, including immune functions can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy. Checkpoint inhibitors block different proteins from binding to tumor cells, allowing the immune system s T cells to kill the tumor. ....

Selma-masri , V-foundation , Uc-irvine-school-of-medicine , Johnson , Department-of-biological-chemistry , National-cancer-institute , Nature-immunology , Bridget-fortin ,

Cancer treatment may work best at the right time of day

"Our findings demonstrate the pivotal role of the circadian clock in enhancing immune checkpoint inhibitor therapy." ....

Irvine , California , United-states , Selma-masri , University-of-california , National-cancer-institute , Johnson , V-foundation , Nature-immunology , Bridget-fortin ,

Circadian Clock Boosts Cancer Immunotherapy, UCI Study Finds

Circadian Clock Boosts Cancer Immunotherapy, UCI Study Finds
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United-states , Irvine-school , California , Orange-county , Irvine , American , Howard-gillman , Selma-masri , Uc-irvine-school-of-medicine , Department-of-biological-chemistry , Johnson , University-of-california

Study reveals circadian clock can be leveraged to enhance cancer immunotherapy

Study reveals circadian clock can be leveraged to enhance cancer immunotherapy
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Irvine , California , United-states , Irvine-school , Bridgetm-fortin , Selma-masri , Uc-irvine-school-of-medicine , University-of-california , Department-of-biological-chemistry , Nature-immunology , Bridget-fortin ,

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy
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Irvine , California , United-states , Irvine-school , Selma-masri , Johnson , Uc-irvine-school-of-medicine , University-of-california , Department-of-biological-chemistry , National-cancer-institute , V-foundation , Nature-immunology