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Low-Dose Amitriptyline May Improve IBS Symptoms as Second-Line Treatment

The tricyclic antidepressant amitriptyline is an efficacious second-line treatment option for IBS symptoms. ....

Irritable Bowel Syndrome , Second Line Treatment , Scoring Symptom ,

GSK's Belantamab Mafodotin Shows Promise as Second-Line Treatment for Multiple Myeloma in Phase III Trial

GSK's Belantamab Mafodotin Shows Promise as Second-Line Treatment for Multiple Myeloma in Phase III Trial
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Treatment Choices for Recurrent dMMR Endometrial Cancer

Exploring treatment options for patients with recurrent mismatch repair deficient endometrial cancer, including the choice between single-agent checkpoint inhibitors and chemo-immunotherapy combinations, with insights from GARNET and KEYNOTE-158 studies. ....

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Amitriptyline Use Nearly Doubles Symptom Improvement in IBS

A large trial of low-dose amitriptyline resulted in nearly twice as many people reporting symptom relief for IBS as placebo, with researchers suggesting that GPs should be offer the drug more often. ....

United Kingdom , Glasgow City , Judith Danby , Hazel Everitt , Alexander Ford , United Kingdom National Institute For Health , Care Research , University Of Southampton , National Institute For Health , University Of Leeds , Royal College , Irritable Bowel Syndrome , Second Line Treatment , General Practitioners , Annual Conference , United European Gastroenterology , Medscape Medical , National Institute , Care Excellence , Scoring System , Irritable Bowel Syndrome Ibs , Irritable Bowel Syndrome , United Kingdom Site Content , Cyclic Antidepressant , Tricyclic Antidepressant , Ca Tricyclic Antidepressant ,

Low-Dose Amitriptyline Offers Viable Second-Line Treatment for IBS

Results from the phase 3 ATLANTIS study showed amitriptyline was superior to placebo across multiple symptom-based outcomes for patients with IBS. ....

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