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New insights into coronavirus E channel could lead to antiviral drugs

The genome of the SARS-CoV-2 virus encodes 29 proteins, one of which is an ion channel called E. This channel, which transports protons and calcium ions, induces infected cells to launch an inflammatory response that damages tissues and contributes to the symptoms of Covid-19. ....

United States , Mei Hong , Joao Medeiros Silva , Noah Somberg , Megan Craig , Aurelio Dregni , Pu Duan , University Of California At San Francisco , National Institutes Of Health , School Of Science Sloan Fund , San Francisco , National Institutes , Science Sloan , Covid 19 , Ton Channel , Amino Acid , Antiviral Drug , Ars Cov 2 ,

New Covid Drugs Possible by Targeting Coronavirus Ion Channel

New Covid Drugs Possible by Targeting Coronavirus Ion Channel
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United States , Joao Medeiros Silva , Noah Somberg , Mei Hong , Pu Duan , Aurelio Dregni , School Of Science Sloan Fund , University Of California At San Francisco , National Institutes Of Health , San Francisco , National Institutes , Science Sloan ,

Targeting a coronavirus ion channel could yield new Covid-19 drugs

MIT chemists discovered the structure of the “open” state of the coronavirus E channel, which contributes to the inflammation seen in cells of Covid-19 patients. The structure could guide researchers in developing antiviral drugs that block the channel and help prevent inflammation. ....

United States , Joao Medeiros Silva , Aurelio Dregni , Pu Duan , Mei Hong , Noah Somberg , University Of California At San Francisco , School Of Science Sloan Fund , National Institutes Of Health , San Francisco , National Institutes , Science Sloan , Coronaviruse Channel , Coronavirus Research , Ars Cov 2 Research , Mei Hong , Joao Medeiros Silva ,