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Combined advances in haematopoietic cell transplantation (HCT) and intensive care management have improved the survival of patients with haematological malignancies admitted to the intensive care unit. In cases of refractory respiratory failure or refractory cardiac failure, these advances have led to a renewed interest in advanced life support therapies, such as extracorporeal membrane oxygenation (ECMO), previously considered inappropriate for these patients due to their poor prognosis. Given the scarcity of evidence-based guidelines on the use of ECMO in patients receiving HCT and the need to provide equitable and sustainable access to ECMO, the European Society of Intensive Care Medicine, the Extracorporeal Life Support Organization, and the International ECMO Network aimed to develop an expert consensus statement on the use of ECMO in adult patients receiving HCT. ....
The Trinidad and Tobago Guardian is the longest running daily newspaper in the country, marking its centenary in 2017. The paper started life as the Trinidad Guardian on Sunday 2nd September 1917 by the newly formed Trinidad Publishing Company Limited. ....
Although crude mortality did not differ between variants, adjusted risk of death was highest for patients treated with ECMO infected with the delta variant of SARS-CoV-2. The higher virulence and poorer outcomes associated with the delta strain might relate to higher viral load and increased inflammatory response syndrome in infected patients, reinforcing the need for a higher rate of vaccination in the population and updated selection criteria for ECMO, should a new and highly virulent strain of SARS-CoV-2 emerge in the future. ....
Improvements in the acute management of critically ill patients have contributed to increased survival in the intensive care unit (ICU), yet up to two-thirds of survivors after mechanical ventilation struggle with post-intensive care syndrome, which consists of new or worsened cognitive impairment, physical disability, or mental health disorders. Of these, cognitive impairment affects a third of survivors and persists a year or more after critical illness;1 however, little is known about the pathogenesis of post-intensive care syndrome, and evidence-based treatments are scarce. ....