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ENHERTU® ▼ (TRASTUZUMAB DERUXTECAN) NOW AVAILABLE VIA THE CANCER DRUGS FUND FOR THE TREATMENT OF HER2 POSITIVE METASTATIC BREAST CANCER


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ENHERTU® ▼ (TRASTUZUMAB DERUXTECAN) NOW AVAILABLE VIA THE CANCER DRUGS FUND FOR THE TREATMENT OF HER2 POSITIVE METASTATIC BREAST CANCER
April 20, 2021 GMT
Daiichi Sankyo UK, Limited
(hereafter, Daiichi Sankyo) and AstraZeneca UK today welcome the news that the National Institute for Health and Care Excellence (NICE) has recommended Enhertu ® (trastuzumab deruxtecan) for use within the Cancer Drugs Fund (CDF) as an option for treating HER2 positive unresectable or metastatic breast cancer in adults who have received two or more prior anti-HER2 based therapies.
In the UK, almost 54,000 cases of breast cancer in women are diagnosed annually, with an estimated one in five cases being HER2 positive. 1,2,3 The impact of the disease is significant, with breast cancer responsible for approximately 12,000 deaths per year. 1 There are an estimated 35,000 people living with ....

United Kingdom , Daiichi Sankyo , Jo Taylor , Iqbaln Iqbal , Melo Gagliato , Alistair Gordon , Haran Maheson , Karun Krishna , Peter Schmid , England Cancer Drugs Fund , Daichi Sankyo United Kingdom Ltd , World Health Organization , Government Affairs , National Institute For Health , Cancer Drugs Fund , Corporate Communications , Daiichi Sankyo Group , National Comprehensive Cancer Network , Barts Cancer Institute , Scottish Medicines Consortium , Sankyo United Kingdom , Astrazeneca United Kingdom , National Institute , Care Excellence , Professor Peter Schmid , Barts Cancer ,

Daiichi Sankyo Company, Limited: Phase 1/2 Trial Initiated for Daiichi Sankyo's Menin Inhibitor DS-1594 in Patients with Acute Myeloid Leukemia and Acute Lymphoblastic Leukemia


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Daiichi Sankyo Company, Limited (hereafter Daiichi Sankyo) today announced the first patient has been dosed in the first-in-human phase 1/2 study of DS-1594, a selective small-molecule menin inhibitor, in adults with relapsed/refractory acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The trial is being conducted by The University of Texas MD Anderson Cancer Center under an existing strategic research collaboration.
Inhibition of the menin protein is being studied as a novel treatment approach for acute leukemias with MLL rearrangement (MLLr) or NPM1 mutation (NPM1m), two gene alterations that drive cancer development and growth.
1 MLLr occurs in approximately 5 to 10% of acute leukemia patients and is associated with aggressive disease, reduced treatment response and poor prognosis. ....

United States , Masashi Kawase , Arnaud Lesegretain , Daiichi Sankyo , Daiichi Sankyo Europe Gmb , Jennifer Brennan , Daiichi Sankyo Co Ltd , Plexxikon Inc , Daiichi Sankyo Inc , Daiichi Sankyo Company , University Of Texas Md Anderson Cancer Center , Daiichi Sankyo Group , Leukemia Lymphoma Society , Cancer Center , Vice President , Alpha Portfolio , Acute Myeloid Leukemia , Acute Lymphoblastic Leukemia , Daiichi Sankyo Cancer Enterprise , Sankyo Group , Pharma Innovator , Competitive Advantage , Population Fact Sheet , Updated November , Leukemia Facts , Acute Myeloid ,

Daiichi Sankyo Company, Limited: DESTINY-CRC02 Phase 2 Trial of ENHERTU Initiated in Patients with HER2 Overexpressing Advanced Colorectal Cancer


Daiichi Sankyo Company, Limited: DESTINY-CRC02 Phase 2 Trial of ENHERTU Initiated in Patients with HER2 Overexpressing Advanced Colorectal Cancer
Interstitial Lung Disease Pneumonitis
Severe, life-threatening, or fatal interstitial lung disease (ILD), including pneumonitis, can occur in patients treated with ENHERTU. Advise patients to immediately report cough, dyspnea, fever, and/or any new or worsening respiratory symptoms. Monitor patients for signs and symptoms of ILD. Promptly investigate evidence of ILD. Evaluate patients with suspected ILD by radiographic imaging. Consider consultation with a pulmonologist. For asymptomatic ILD/pneumonitis (Grade 1), interrupt ENHERTU until resolved to Grade 0, then if resolved in =28 days from date of onset, maintain dose. If resolved in >28 days from date of onset, reduce dose one level. Consider corticosteroid treatment as soon as ILD/pneumonitis is suspected (e.g., =0.5 mg/kg/day prednisolone or equivalent). For symptomatic ILD/ ....

United States , United Kingdom , Masashi Kawase , Daiichi Sankyo , Daiichi Sankyo Europe Gmb , Don Murphy , Plexxikon Inc , Daiichi Sankyo Company , Oncology Development , Daiichi Sankyo Inc , World Health Organization , Clinical Development Program , Daiichi Sankyo Co Ltd , Daiichi Sankyo Group , Gilles Gallant , Senior Vice President , Global Head , Interstitial Lung Disease , Prescribing Information , Clinical Cancer Advances , Molecular Profiling Driving Progress , Breakthrough Therapy Designation , Astrazeneca Collaboration , Safety Information , Metastatic Gastric , Absolute Neutrophil Count ,

New Survey Reveals Nearly Half of Women Are Unfamiliar with a Condition that Affects Up to Five Million Adults in the U.S.¹


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BASKING RIDGE, N.J., Feb. 17, 2021 /PRNewswire/ Daiichi Sankyo, Inc. today announced new survey results that reveal concerning gaps in women s knowledge of Iron Deficiency Anemia (IDA), the most common type of anemia that can impact one in five women of childbearing age.
2 According to a national survey as part of the 
Get Iron Informed initiative, nearly half of women age 18-65 (45%) are unfamiliar with IDA. The survey also revealed that, on average, women with IDA experienced a delay in diagnosis of 3.9 years from the onset of symptoms.
IDA is more common in women, ....

United States , New Jersey , Stephanie Martin , Daiichi Sankyo , Matt Coppola , Daiichi Sankyo Inc , Daiichi Sankyo Group , National Heart , Blood Institute , Harris Poll , Iron Informed , Sankyo Group , Pharma Innovator , Competitive Advantage , Basking Ridge , Iron Definitely Anemia , Cold Spring Harbor Perspectives , Accessed December , ஒன்றுபட்டது மாநிலங்களில் , புதியது ஜெர்சி , மாற்றாந்தாய் மார்டின் , தய்ச்சி சாங்கியோ , மேட் கொப்போலா , தய்ச்சி சாங்கியோ இன்க் , தய்ச்சி சாங்கியோ குழு , தேசிய இதயம் ,