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Ultrasound Neuromodulation Shows Promise to Treat Pulmonary Hypertension, Feinstein Institutes Research

Ultrasound Neuromodulation Shows Promise to Treat Pulmonary Hypertension, Feinstein Institutes Research
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American
Stefanos-zafeiropoulos
Kevinj-tracey
Stavros-zanos
Sangeetas-chavan
American-heart-association
Ge-research
Feinstein-institutes-for-medical-research
Circulation-research
Institute-of-bioelectronic-medicine
Feinstein-institute-of-bioelectronic-medicine

Optogenetic Study Identifies Therapeutic Target for Inflammatory Diseases and Neuropathic Pain

Combining optogenetics, cre recombination mediated neuron-specific mutations, sciatic nerve-injury, and disease models of arthritis, with direct measurements of inflammation and neuropathic pain, scientists at the Feinstein Institutes show that the release of the nociceptor protein HMGB1 is required to mediate neuropathic pain (allodynia) and inflammation. The preclinical study provides direct evidence that nociceptor-related pain can be prevented by targeting HMGB1 in new therapeutic approaches to treat neuroinflammatory diseases.

Kevinj-tracey
Chuan-yang
Sangeetas-chavan
Proceedings-of-the-national-academy-sciences
Institute-of-bioelectronic-medicine
Feinstein-institutes
National-academy
Bioelectronic-medicine
ஹுவான்-யாங்
ஃபைன்ஸ்டீன்-நிறுவனங்கள்
தேசிய-கலைக்கழகம்

Feinstein Institutes Bioelectronic Medicine Researchers Control Nerve to Turn On/Off Inflammation

Feinstein Institutes Bioelectronic Medicine Researchers Control Nerve to Turn On/Off Inflammation
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New-york
United-states
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America
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Kevinj-tracey
Chuan-yang
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