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Identifying Cancer Genes' Multiple Personalities

A new method using the gene-editing tool CRISPR-Cas9 has been developed to model liver cancer tumor subtypes caused by mutations in the same genes. By targeting a single section of the mouse gene, Ctnnb1, researchers were able to produce two distinct tumor subtypes, enhancing protein activity to promote tumor growth, which could allow for the development of new therapeutic interventions in the future. ....

Semir Beyaz , Cold Spring Harbor Laboratory Assistant Professor , Cold Spring Harbor Laboratory , Cold Spring Harbor , Samuel Diamond , Neuroscience Newsletter ,

Got junk food on the brain? These cells may be to blame

/PRNewswire/ A region of the brain called the amygdala is responsible for powerful emotions like fear. Now, researchers have found the amygdala may also be. ....

Bo Li , Semir Beyaz , Tobias Janowitz , Stephen Shea , Cold Spring Harbor Laboratory , Spring Harbor Laboratory , Professor Stephen Shea , Professor Semir Beyaz , Nobel Prize , Samuel Diamond , Spring Harbor ,