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New PET tracer detects hallmark of Alzheimer's disease years before symptoms emerge


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IMAGE: Tau accumulation over one year measured in composite A) mesial temporal ROI; and B) temporoparietal ROI in cognitively unimpaired participants (blue) and cognitively impaired participants (red). The CI group included.
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Credit: Image created by N Krishnadas et al. Florey Department of Neurosciences & Mental Health, The University of Melbourne; Department of Molecular Imaging & Therapy, Austin Hospital, Melbourne.
Reston, VA (Embargoed until 7:30 p.m. EDT, Monday, June 14, 2021) A novel positron emission tomography (PET) radiotracer has been shown to effectively measure increases in brain tau a distinguishing characteristic of Alzheimer s disease before any symptoms of the disease are observed. With the potential to measure increases in tau over a long period of time, this tracer offers an important tool to assess the effectiveness of Alzheimer s disease treatments in clinical trials. This research was presented at the Society of Nu ....

New South Wales , Kun Huang , Natasha Krishnadas , Rachel Mulligan , Samantha Burnham , Vincent Dore , Christopher Rowe , Svetlana Bozinovski , Regan Tyrrell , Victor Villemagne , Biomedical Imaging Health Biosecurity Flagship , Australian Dementia Network , Austin Health , University Of Melbourne , Florey Department Of Neurosciences Mental Health , Society Of Nuclear Medicine , Australian Dementia Network Adne , Department Of Molecular Imaging Therapy , Nuclear Medicine , Molecular Imaging , Florey Department , Mental Health , Austin Hospital , Imaging Health , Biosecurity Flagship , Fiona Lamb ,