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IASO Bio's Equecabtagene Autoleucel for Refractory Myasthenia Gravis (MG) Case Report Published in EMBO Molecular Medicine

/PRNewswire/ On February 26, 2024, the impactful international academic journal, EMBO Molecular Medicine, published the clinical data of the fully human. ....

Wei Wang , Equecabtagene Autoleucel , Demyelinating Polyneuropathy , China National Medical Products Administration , Huazhong University Of Science , Tongji Medical College , Acetylcholine Receptor , Lipoprotein Receptor Related Protein , Ryanodine Receptor , Tongji Hospital , Huazhong University , Release Syndrome , Cell Associated Neurotoxicity Syndrome , Myasthenia Gravis Activities , Daily Living Score , Quantitative Myasthenia Gravis Score , Myasthenia Gravis Quality , Life Score , Modified Rankin Score , Myasthenia Gravis , Immune Mediated Necrotizing Myelopathy , Chronic Inflammatory Demyelinating Polyneuropathy , New Drug Application , National Medical Products Administration ,

ARMGO Pharma Publishes Positive Phase 1b Trial Results of Rycal® ARM210 for the Treatment of Ryanodine Receptor 1 Related Myopathies

ARMGO Pharma Publishes Positive Phase 1b Trial Results of Rycal® ARM210 for the Treatment of Ryanodine Receptor 1 Related Myopathies
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United States , Les Laboratoires Servier , Stefan Klotter , Michaelf Goldberg , Joshua Todd , National Institutes Of Health , Clinical Center Bench To Bedside Award , National Institute Of Neurological Disorders , Intramural Research Programs , Pharma Inc , Development Agreement , Research Council , Publishes Positive Phase , Trial Results , Ryanodine Receptor , Medical Research Council , National Institute , Neurological Disorders , National Institutes , Cooperative Research , Gene Marcantonio , Chief Executive Officer , Center Bench , Bedside Award , Les Laboratoires , Renna Foufouni ,

ARMGO Pharma Publishes Positive Phase 1b Trial Results of Rycal® ARM210 for the Treatment of Ryanodine Receptor 1 Related Myopathies

ARMGO Pharma Publishes Positive Phase 1b Trial Results of Rycal® ARM210 for the Treatment of Ryanodine Receptor 1 Related Myopathies
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United States , Les Laboratoires Servier , Joshua Todd , Michaelf Goldberg , National Institutes Of Health , Clinical Center Bench To Bedside Award , Columbia University , Pharma Inc , Research Council , Intramural Research Programs , National Institute Of Neurological Disorders , Development Agreement , Publishes Positive Phase , Trial Results , Ryanodine Receptor , Medical Research Council , National Institute , Neurological Disorders , National Institutes , Cooperative Research , Gene Marcantonio , Chief Executive Officer , Center Bench , Bedside Award , Les Laboratoires , Renna Foufouni ,

ARMGO Pharma Enrolls First Patient in Phase 2 Trial of ARM210 for the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia

Trial to investigate the safety and efficacy of ARM210 for the treatment of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT). ....

United States , Noord Holland , Danielle Ellis , Pharma Inc , Amsterdam University Medical Center , Mayo Clinic , Ryanodine Receptor , Related Myopathy , Gene Marcantonio , Chief Executive Officer ,

Frontiers | The Case for, and Challenges of, Human Cardiac Tissue in Advancing Phosphoprotein Research

Cardiovascular disease (CVD) and stroke affect over 92 million Americans and account for nearly 1 out of 3 deaths in the US. The use of animal models in cardiovascular research has led to considerable advances in treatment and in our understanding of the pathophysiology of many CVDs. Still, animals may not fully recapitulate human disease states; species differences have long been postulated to be one of the main reasons for a failure of translation between animals and humans in drug discovery and development. Indeed, it has become increasingly clear over the past few decades that to answer certain biomedical questions, like the physiological mechanisms that go awry in many human CVDs, animal tissues may not always be the best option to use. While human cardiac tissue has long been used for laboratory research, published findings often contradict each other, leading to difficulties in interpretation. Current difficulties in utilizing human cardiac tissue include differences in acquisit ....

United States , New South Wales , Ohio State University , Evelyn Fein , Acta Physiol , Sachs Akad Wiss , Ptms Aebersold , Springer Verlag , Van Eyk , American Heart Association , National Institutes Of Health , Division Of Cardiac Surgery , Ohio State University Human Heart Resource , Mcgraw Hill , Ohio State University Wexner Medical Center , Sydney Heart Bank , Modifications Expand , Human Genome Project , Human Proteome Project , Frank Starling , Ryanodine Receptor , Myosin Light , Critical Need , Studies Involving Human Cardiac , Tissue Collection Processes Differ From Animals , Septal Myectomy ,