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GlaxoSmithKline and Sanofi Pasteur vaccine delayed until late 2021


GlaxoSmithKline and Sanofi Pasteur vaccine delayed until late 2021
From CNN s Martin Goillandeau in London
An employee works at a GlaxoSmithKline factory in Saint-Amand-les-Eaux, France, on December 3, where the adjuvant for Covid-19 vaccines will be manufactured. Francois Lo Presti/AFP/Getty Images
British and French pharmaceutical giants GlaxoSmithKline and Sanofi Pasteur said Friday the release of their coronavirus vaccine would be delayed until late 2021 after interim results showed “insufficient immune response” in the elderly.
“Insufficient response in older adults demonstrates the need to refine the concentration of antigen in order to provide high-level immune response across all age groups,” a joint press release on their websites read. ....

United States , Singapore General , United Arab Emirates , Hong Kong , United Kingdom , Saint Amand Les Eaux , Nord Pas De Calais , City Of , San Francisco , Noord Holland , Soult Ukpyolsi , South Korea , Krung Thep Mahanakhon , Novosibirskaya Oblast , Novgorodskaya Oblast , South Korean , Akanksha Sharma , Anthony Fauci , Chandler Thornton , Thomas Triomphe , Roslan Rahman , Martin Goillandeau , Wolf Blitze , Roger Connor , Paul Offit , Mary Ilyushina ,

UK TOP NEWS SUMMARY: UK's Johnson Says No Deal A


UK TOP NEWS SUMMARY: UK s Johnson Says No Deal A Strong Possibility
Fri, 11th Dec 2020 11:17
(Alliance News) - The following is a summary of top news stories Friday.
COMPANIES
GlaxoSmithKline and Sanofi said their Covid-19 vaccine has been delayed to the end of 2021 after interim study result found an insufficient response in older patients. The phase 1/2 study s interim results showed an immune response that was comparable to patients who had recovered from Covid-19 in adults aged 18 to 49, but a low immune response in older adults. The two firms plan to begin a phase 2b study in February 2021 with an improved antigen formulation, which will include a proposed comparison with an already authorised Covid-19 vaccine. With positive data, a global phase 3 study could begin in the second 2021 quarter, and positive results from that would lead to regulatory submissions in the second half of 2021. Overall, this means the vaccine potential availability has moved to the ....

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AstraZeneca to test if its vaccine works better combined with Russia's Sputnik V


The collaboration with AstraZeneca may help boost confidence in Sputnik V, amid scepticism over the speed of its rollout and the scope and transparency of data from clinical trials. Russia’s defence ministry claims the vaccine is a victim of a foreign financed “information sabotage” campaign.
The Kremlin hailed Sputnik V as the world’s first registered coronavirus vaccine in August, when Russian regulators approved it before phase three trials had even begun.
“We believe the poor methodological quality, design flaws in the study, errors in data analysis, and poor description of the study cast doubt on the main conclusions about the safety and efficacy of the vaccine,” three vice-presidents of Russia’s Society for Evidence-Based Medicine said of the available Sputnik V test data. ....

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