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New photoreceptors from human pluripotent stem cells restores sight to injured retinas Tens of millions of people worldwide are affected by diseases like macular degeneration or have had accidents that permanently damage the light-sensitive photoreceptors within their retinas that enable vision. The human body is not capable of regenerating those photoreceptors, but new advances by medical researchers and engineers at the University of Wisconsin–Madison may provide hope for those suffering from vision loss. They described their work today in the journal Science Advances. Researchers at UW–Madison have made new photoreceptors from human pluripotent stem cells. However, it remains challenging to precisely deliver those photoreceptors within the diseased or damaged eye so that they can form appropriate connections, says David Gamm, director of the McPherson Eye Research Institute and professor of ophthalmology and visual sciences at the UW School of Medicine and Public Health.

United statesUniversity of wisconsinJuhwan leeEmily hendersonAllison ludwigDavid gammZhenqiang jack maRuosen alex xieShaoqin sarah gongMinkyu leePublic healthWisconsin institute for discoveryWisconsin alumni research foundationMcpherson eye research instituteUw school of medicineWisconsin institute