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'Hunker down' stress impacts gene expression


The chronic stress of living in neighborhoods with high rates of violence and poverty alters gene activity in immune cells, according to a new study of low-income single Black mothers on the South Side of Chicago.
The changes in stress-related gene expression reflect the body’s “hunker down” response to long-term threat, a physiological strategy for lying low and considering new actions rather than launching an immediate “fight-or-flight” response. This has implications for health outcomes in communities of color and other marginalized populations, said researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Kentucky and UCLA. The researchers published the study in the journal Psychoneuroendocrinology. ....

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'Hunker down' stress genes boosted in women who live in violent neighborhoods


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IMAGE: Living in a violent neighborhood increased stress-related gene activity in low-income Black mothers, a study from the University of Illinois and collaborators found.
Illinois professors pictured, from left: Sandra Rodriguez-Zas, animal.
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Credit: Photo by L. Brian Stauffer
CHAMPAIGN, Ill. The chronic stress of living in neighborhoods with high rates of violence and poverty alters gene activity in immune cells, according to a new study of low-income single Black mothers on the South Side of Chicago.
The changes in stress-related gene expression reflect the body s hunker down response to long-term threat, a physiological strategy for lying low and considering new actions rather than launching an immediate fight-or-flight response. This has implications for health outcomes in communities of color and other marginalized populations, said researchers at the University of Illinois Urbana-Champaign and collaborators at the ....

United States , University Of Illinois , Clare Rittschof , Ruby Mendenhall , Meggan Lee , Steve Cole , Andrew Greenlee , Gene Robinson , Kedir Turi , Sandra Rodriguez , Population Health , College Of Liberal Arts , Carlr Woese Institute For Genomic Biology , Carle Illinois College Of Medicine , Center On Biodemography , Vanderbilt University , University Of Kentucky , University Of Illinois Urbana Champaign , South Side , Illinois Urbana Champaign , African American , Carle Illinois College , Genomic Biology , Liberal Arts , Sandra Rodriguez Zas , Margaret Romano Professorial Scholarship ,