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New research highlights importance of thymus in successful pregnancies


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New research highlights importance of thymus in successful pregnancies
How the immune system adapts to pregnancies has puzzled scientists for decades. Now, findings from an international group of researchers, led by researchers at Karolinska Institutet in Sweden, reveal important changes that occur in the thymus to prevent miscarriages and gestational diabetes. The results are published in the journal Nature.
The thymus is a central organ of the immune system where specialised immune cells called T lymphocytes mature. These cells, commonly referred to as T cells, then migrate into the blood stream and tissues to help combat pathogens and cancer. An important T cell subset, known as a regulatory T cell or Treg, is also produced in the thymus. The main function of a Treg is to help regulate other immune cells. ....

United Kingdom , British Columbia , Josefm Penninger , Sabine Dekan , Alexandra Kautzky Willer , Dagmar Bancher Todesca , Iris Uribesalgo , Juergen Harreiter , Thomas Penz , Magdalena Paolino , Shane Jf Cronin , Rubina Koglgruber , Graham Anderson , Lukas Kenner , Karolinska Institutet , Christoph Bock , Maria Novatchkova , Verena Sigl , Georga Holl , Michael Schuster , Juanp Fededa , Josef Penninger , Blanka Pranjic , Esther Rauscher , Andrea White , Ragnar Soderberg Foundation ,

New research highlights the importance of the thymus in successful pregnancies


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IMAGE: Magdalena Paolino, assistant professor and team leader at the Department of Medicine Solna, Karolinska Institutet.
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Credit: Ragnar Söderberg Foundation
How the immune system adapts to pregnancies has puzzled scientists for decades. Now, findings from an international group of researchers, led by researchers at Karolinska Institutet in Sweden, reveal important changes that occur in the thymus to prevent miscarriages and gestational diabetes. The results are published in the journal
Nature.
The thymus is a central organ of the immune system where specialised immune cells called T lymphocytes mature. These cells, commonly referred to as T cells, then migrate into the blood stream and tissues to help combat pathogens and cancer. An important T cell subset, known as a regulatory T cell or Treg, is also produced in the thymus. The main function of a Treg is to help regulate other immune cells. ....

United Kingdom , British Columbia , Josefm Penninger , Sabine Dekan , Alexandra Kautzky Willer , Dagmar Bancher Todesca , Iris Uribesalgo , Juergen Harreiter , Thomas Penz , Magdalena Paolino , Shane Jf Cronin , Rubina Koglgruber , Graham Anderson , Lukas Kenner , Karolinska Institutet , Christoph Bock , Maria Novatchkova , Verena Sigl , Georga Holl , Michael Schuster , Juanp Fededa , Josef Penninger , Blanka Pranjic , Esther Rauscher , Andrea White , Ragnar Soderberg Foundation ,