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XORTX Announces New Clinical Advisory Board Member

CALGARY, Alberta, March 27, 2024 (GLOBE NEWSWIRE) XORTX Therapeutics Inc. ( ....

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XORTX Announces New Clinical Advisory Board Member - XORTX Therapeutics (NASDAQ:XRTX)

CALGARY, Alberta, March 27, 2024 (GLOBE NEWSWIRE) XORTX Therapeutics Inc. ("XORTX" or the "Company") (NASDAQ:XRTX, TSXV:XRTX, Frankfurt: ANUA WKN: A3UNZ)), a biopharmaceutical company focused on developing ....

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XORTX Therapeutics Inc (XRTX) Appoints Ronald Perrone to its Board

XORTX Therapeutics Inc (XRTX) Appoints Ronald Perrone to its Board
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XORTX Announces New Clinical Advisory Board Member

XORTX Announces New Clinical Advisory Board Member
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Metformin Well Tolerated in Polycystic Kidney Disease

email article
Metformin was both safe and well tolerated in patients with autosomal dominant polycystic kidney disease (ADPKD), the phase II TAME PKD trial found.
The parallel-group, randomized trial of 97 participants found no significant increase in gastrointestinal symptoms over 24 months, according to Ronald Perrone, MD, of Tufts Medical Center in Boston, and colleagues.
As measured by the Gastrointestinal Symptoms Rating Scale (GSRS), patients on metformin also didn t see any gastrointestinal tolerability issues compared with those on placebo.
Lactic acidosis and hypoglycemia were not found to be problematic, Perrone said during a presentation of the late-breaking findings at the virtual National Kidney Foundation Spring Clinical Meeting. However, there was no evidence signal for efficacy to slow progression. ....

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