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New Insights into Ancient Gatekeeper Protein Complex endocytosis March 3, 2021 Gatekeeper protein complexes at the outer boundaries of cells make life possible by regulating the passage of key molecules such as nutrients into and out of the cell. Scientists in Belgium and the Czech Republic have revealed new structural and functional insights on an ancient, evolutionarily conserved protein complex that makes it possible for cells to wrap their membranous arms around and bring essential biomolecules into the cell a process called endocytosis. The structure and function of cells with nuclei (eukaryotic cells) depend on endocytosis for the continuous exchange of biomolecules through membranes. ....