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Neuron Model Paves Way For New Alzheimer s Therapies

Neuron Model Paves Way For New Alzheimer s Therapies
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Judithb resnickShiaoching gongCeleste parra bravoHeather lindseyNational instituteWeill cornell graduate school of medical sciencesNational institute of neurological disordersRobert appel alzheimer disease research instituteNational institute onTau consortiumAppel instituteNational institutes of healthResearch instituteWeill cornell medicineRobert appel alzheimerDisease research institute

Neuron model paves way for new Alzheimer s therapies

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain – a process that drives cognitive decline in Alzheimer’s disease and frontotemporal dementia.

Shiaoching gongCeleste parra bravoJudithb resnickWeill cornell graduate school of medical sciencesNational instituteTau consortiumNational institutes of healthNational institute of neurological disordersAppel instituteNational institute onResearch instituteRobert appel alzheimer disease research instituteWeill cornell medicineRobert appel alzheimerDisease research instituteDistinguished professor

Human Neuron Model Advances Alzheimer s Therapy Potential

Human Neuron Model Advances Alzheimer s Therapy Potential
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Celeste parra bravoShiaoching gongJudithb resnickAppel institute at weill cornell medicineResearch institute at weill cornell medicineRobert appel alzheimer disease research instituteWeill cornell graduate school of medical sciencesWeill cornell medicineRobert appel alzheimerDisease research instituteDistinguished professorNeurodegenerative diseasesFeil family brainMind research instituteWeill cornellWeill cornell graduate school

Human neuron model identifies potential therapeutic targets for Alzheimer s disease

Weill Cornell Medicine scientists have developed an innovative human neuron model that robustly simulates the spread of tau protein aggregates in the brain-;a process that drives cognitive decline in Alzheimer's disease and frontotemporal dementia.

Celeste parra bravoShiaoching gongJudithb resnickRobert appel alzheimer disease research instituteAppel instituteWeill cornell graduate school of medical sciencesCornell medicineRobert appel alzheimerDisease research instituteDistinguished professorNeurodegenerative diseasesFeil family brainMind researchWeill cornellWeill cornell graduate schoolMedical sciences

Study reveals non-coding genetic variants associated with Alzheimer s disease functioning in microglia

Scientists studying Alzheimer's disease (AD) have identified thousands of genetic variants in the genome in the development of this progressive neurodegenerative disease.

United statesSan franciscoYun liDanielle ellisRobert appel alzheimer disease research instituteUniversity of californiaGillings school of global public healthUniversity of north carolina at chapel hillSchool of medicineInstitute of human geneticsDepartment of neurologyWeill cornell medical collegeNorth carolinaChapel hillGlobal publicYin shen