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1. In this randomized controlled trial, rifapentine was associated with a reduced incidence of leprosy in household contacts compared to rifampin and no intervention. 2. No severe adverse events were associated with rifapentine or rifampin. Evidence Rating Level: 1 (Excellent) Study Rundown: Leprosy is a chronic infection caused by Mycobacterium leprae, mainly affecting low-resource areas. ....
The following products have been recommended for use by the Expert Review Panel (ERP): Rifapentine 300mg tablets Al/Al strip pack manufactured by Lupin, India; Rifapentine/Isoniazid 300/300mg Al/Al strip pack manufactured by Lupin, India ....