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Pooping out miracles: scientists reveal mechanism behind fecal microbiota transplantation

In a study published in Gastroenterology – Researchers at Osaka City University and The Institute for Medical Science, The University of Tokyo, in collaboration with Brigham and Women's Hospital in Boston, report the intestinal bacterial and viral metagenome information from the fecal samples of patients with recurrent Clostridioides difficile infection (rCDI). This comprehensive analysis reveals the bacteria and phages involved in pathogenesis in rCDI, and their remarkable pathways important for the recovery of intestinal flora function. ....

United States , Kosuke Fujimoto , Satoshi Uematsu , Seiya Imoto , Institute For Medical Science , University Of Tokyo , Researchers At Osaka City University , Osaka City University , Medical Science , Professor Satoshi Uematsu , ஒன்றுபட்டது மாநிலங்களில் , நிறுவனம் க்கு மருத்துவ அறிவியல் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , ஆராய்ச்சியாளர்கள் இல் ஒசகக நகரம் பல்கலைக்கழகம் , ஒசகக நகரம் பல்கலைக்கழகம் , மருத்துவ அறிவியல் ,

Study reveals mechanism behind "Fecal Microbiota Transplantation"

Study reveals mechanism behind “Fecal Microbiota Transplantation”
Clostridioides difficile infection (rCDI) occurs in the gut and is caused by the Gram-positive, spore-forming anaerobic bacterium, C. difficile when its spores attach to fecal matter and are transferred from hand to mouth by health care workers.
Patients undergoing antibiotic treatment are especially susceptible as the microorganisms that maintain a healthy gut are greatly damaged by the antibiotics.
Treatment of rCDI involves withdrawing the causative antibiotics and initiating antibiotic therapy, although this can be very challenging. Fecal microbiota transplantation (FMT) is considered an effective alternative therapy as it addresses the issue from the ground up by replacing the damaged microflora with a healthy one through a stool transplant. ....

United States , Kosuke Fujimoto , Satoshi Uematsu , Seiya Imoto , Emily Henderson , Institute For Medical Science , University Of Tokyo , Researchers At Osaka City University , Osaka City University , Medical Science , Principal Investigator , Osaka City , Fecal Microbiota Transplantation , Health Care , ஒன்றுபட்டது மாநிலங்களில் , எமிலி ஹென்டர்சன் , நிறுவனம் க்கு மருத்துவ அறிவியல் , பல்கலைக்கழகம் ஆஃப் டோக்கியோ , ஆராய்ச்சியாளர்கள் இல் ஒசகக நகரம் பல்கலைக்கழகம் , ஒசகக நகரம் பல்கலைக்கழகம் , மருத்துவ அறிவியல் , ப்ரிந்ஸிபல் புலனாய்வாளர் , ஒசகக நகரம் , ஆரோக்கியம் பராமரிப்பு ,