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07.19.21 -- Merck's Efforts To Increase Patient Diversity clinicalleader.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from clinicalleader.com Daily Mail and Mail on Sunday newspapers.
By Renee Simar, Ph.D., Elligo Pediatric Advisory, Board Chair Vaccine clinical trials against COVID-19 in adults are leading the effort before studies begin in children. Although early reports show COVID-19 symptoms tend to be milder in children, some develop severe manifestations of the disease. With an even larger gap in symptomology between adults and children, adult trials will not be easily adaptable to children. Despite decades of progress in pediatric product development, pediatric clinical research remains challenging. A comment from FDA’s Dr. Dianne Murphy in 1999 highlights a relevant keystone during the rapid pace of this pandemic, “We have a very high bar to pass if we are going to enroll children in clinical trials.” ....