In studies using designs addressing sources of bias and confounding, there is no evidence of a survival benefit for cancer trial participants, according to a study published online May 20 in the Journal of the American Medical Association to coincide with the annual meeting of the Society for Clinical Trials, held May 19–22 in Boston.
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Patients participating in clinical trials for anticancer drugs do not gain a survival benefit compared with individuals who received routine care, according to study results published in JAMA.Although trial participants had significantly improved OS when researchers performed a pooled analysis of all the studies evaluated, those benefits diminished when they focused solely on high-quality trials,
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