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Radiology and Radiation Oncology | Imaging Technology News

The four standard views of an individual mammogram were fed into Mirai. The image encoder mapped each view to a vector, and the image aggregator combined the four view vectors into a single vector for the mammogram. In this work, we used a single shared ResNet-18 as an image encoder, and a transformer as our image aggregator. The risk factor predictor module predicted all the risk factors used in the Tyrer-Cuzick model, including age, detailed family history, and hormonal factors, from the mammogram vector. The additive hazard layer combined information from both the image aggregator and risk factors (predicted or given) to predict coherent risk assessments across 5 years (Yr).

Radiology and Radiation Oncology | Imaging Technology News

Methodology for evaluation of tumor cell density (TCD) and allocation of radiotherapy response categories. (A) Virtual graticule of approximately 300 points applied to tumor area on a digital H&E section. (B) Demonstration of TCD point scoring. (C) Box and whisker plot to show the relationship between ΔTCD and American Joint Committee on Cancer (AJCC) Tumour Regression Grade System (TRG). (D, E) Allocation of three radiotherapy response groups according to change in TCD (ΔTCD) for short-course radiotherapy (SCRT) (D) and long-course chemoradiotherapy (LCRT) (E). The Kruskall-Wallis test was used for statistical comparisons. Image courtesy of BMJ

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