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Morning Brief Podcast: Indian Railways: How safe is it to travel?

India’s biggest mover of things – its railways run more than 13,000 trains ferrying close to 400 crore people. Even with the rapid emergence of new and faster trains, the story has lately teetered on the brink of derailment. The Balasore accident, which happened in June, was India’s deadliest train crash in almost three decades. But who is to be blamed? Host Anirban Chowdhury talk about the safety issues with Ravinder Gupta, (Retired) Director General, Safety at Ministry of Railways, S K Choubey, East Coast Railway President - All India Loco Running Staff Association, M M Roly, National Vice President, All India Loco Running Staff Association Southern Railway, and ET’s Twesh Mishra. Listen to the latest episode of the Morning Brief podcast! Credit: CNN-News18 Newsclip, India Today Newsclip and CNN-News18 Newsclip 2. ....

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Одной вакцинации недостаточно: чем может закончиться пандемия Covid-19

Одной вакцинации недостаточно: чем может закончиться пандемия Covid-19
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Frontiers | Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed for twelve inflammatory cytokines using ELISA. Serotyping shows 14 DENV-1, 22 DENV-2, 7 DENV-3 and 33 DENV-4, where DENV-4 was predominant. Among seventy-six, forty-two isolates were successfully sequenced for C-prM region and grouped. A lineage shift was observed in DENV-4 genotype. Irrespective of serotypes, IFNγ was significantly elevated than control and in primary infection indicating its ro ....

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