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Study Suggests Best Strategies for Neonatal Surfactants


One in five infants received surfactant off-label, either for indication or number of administrations.
Adherence to best practice and administration of surfactant within two hours after birth was associated with lower rates of pneumothorax, intraventricular hemorrhage (IVH) grades 3 to 4, and receipt of postnatal corticosteroids in very preterm survivors.
Very early surfactant administration peaking approximately 10 minutes after birth was associated with increased mortality.
Not using surfactant treatment was linked with lower survival in very preterm infants.
However, the authors cautioned that the “observational study design limits the conclusions that can be drawn, and no causality of the described associations can be confirmed.” ....

United States , Karolinska Institutet , Shalmali Pal , Los Angeles , Chiesi Pharma , Rangasamy Ramanathan , University In Ume , Pontus Challis , Keck School , Contributing Writer , Region Stockholm , Childhood Foundation , Swedish Order , ஒன்றுபட்டது மாநிலங்களில் , லாஸ் ஏஞ்சல்ஸ் , கேக்க் பள்ளி , பகுதி ஸ்டாக்‌ஹோல்ம் , குழந்தை பருவம் அடித்தளம் ,