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PureTech Awarded up to $11.4 Million from U.S. Department of Defense to Advance LYT-300 (Oral Allopregnanolone) for Fragile X-associated Tremor/Ataxia Syndrome

Planning underway for Phase 2 trial of LYT-300 in Fragile X-associated Tremor/Ataxia Syndrome

LYT-300 is also being evaluated in a Phase 2a trial for anxiety disorders, and a Phase 2a in patients. ....

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PureTech receives $11.4M award from US Department of Defense

PureTech Health plc has been awarded $11.4 million (£8.9 million) from the US Department of Defense (DoD) to advance its therapeutic candidate for the potential treatment of neurological and neuropsychiatric disorders. ....

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Research: Common Autism Screening Tool Effective but Limited

Research: Common Autism Screening Tool Effective but Limited
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Fragile X neurons develop atypically in chimeric mice | Spectrum

After a brain transplant of reprogrammed human cells, the animals can for the first time recapitulate some neuronal changes seen in people with fragile X syndrome. ....

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The cloudy connection between fragile X and cancer | Spectrum

People with the autism-linked syndrome lack a protein implicated in several cancers, but it’s unclear whether — or how — they are protected from malignancies. ....

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