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A Recipe for Universal Vaccines May 13, 2021• Physics 14, 72 Researchers use nonequilibrium statistical physics methods to guide the design of vaccines that are effective against many strains of a virus, a holy grail of immunology. terovesalainen/stock.adobe.com Vaccines might be optimized by choosing a sequence of different antigens for the initial and booster shots. terovesalainen/stock.adobe.com Vaccines might be optimized by choosing a sequence of different antigens for the initial and booster shots.× Just over a year ago, physicists around the world shifted their research efforts to the field of infectious diseases to help combat the COVID-19 pandemic. In the US, soft-matter physicists trialed a technique for detecting SARS-CoV-2, the virus that causes COVID-19; in Switzerland, high-energy physicists tested an inexpensive ventilator technology that could help sufferers breathe; and in the UK, condensed-matter physicists donated thei ....