This Pearl District Mexican restaurant is known for its handmade corn tortillas, lovingly made by Janet Vargas, or Doña Chapis as sheâs known to the kitchen staff. Vargas combines multiple colors of Three Sisters Nixtamal masaâblue, green, white, yellowâto create multicolored tortillas. Then, she nestles queso oaxaca from Salemâs Don Froylan Creamery inside the tortilla, plus your optional choice of guisado: piquant pollo enchilado, rich cochinita pibil, or earthy champiñones. Dip each bite in nutty, toasty salsa macha (an oil-based blend of peanuts, sesame, garlic, and chileâsee the recipe here) or salsa de aguacate (think a light, creamy, mildly spicy guacamole). Enjoy your quesadillas on Repúblicaâs airy patio, or take them to go.Â