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Nathan C Nickel, Wanda Phillips-Beck and colleagues assess whether First Nations-led COVID-19 protective measures were associated with improved access to COVID-19 testing and vaccination compared to all other Manitobans. ....
Author summary • Human immunodeficiency virus (HIV) drug resistance has implications for antiretroviral treatment strategies and for containing the HIV pandemic because the development of HIV drug resistance leads to the requirement for antiretroviral drugs that may be less effective, less well-tolerated, and more expensive than those used in first-line regimens. • HIV drug resistance studies are designed to determine which HIV mutations are selected by antiretroviral drugs and, in turn, how these mutations affect antiretroviral drug susceptibility and response to future antiretroviral treatment regimens. • Such studies collectively form a vital knowledge base essential for monitoring global HIV drug resistance trends, interpreting HIV genotypic tests, and updating HIV treatment guidelines. • Although HIV drug resistance data are collected in many studies, such data are often not publicly shared, prompting the need to recommend best practices to encourage and st ....
Marina Antillon and colleagues use updated statistical models to estimate the burden of RSV in low- and middle-income countries with the aim of improved targeted prevention strategies. ....
Anke B Witteveen and colleagues synthesise evidence from 123 systematic reviews investigating mental health outcomes during the COVID-19 pandemic. ....
Shekhar Saxena and Cindy Chwa discuss the neglect of care for people living with mental disorders during the pandemic, and highlight relevant implications for policy-makers. ....